Pepto Bismol

By PetMD Editorial on Nov. 7, 2012

Drug Info

  • Common Name: Pepto-Bismol®, Bismatrol®, Kaopectate®, Corrective Suspension®, Bismukote®, Bismupaste®, Mismusol®, Gastro-Cote®
  • Drug Type: Antidiarrheal
  • Used For: Diarrhea, Upset stomach
  • Species: Dogs
  • Administered: Oral liquid, 262 mg tablets
  • How Dispensed: Over the counter
  • FDA Approved: Yes

General Description

Bismuth subsalicylate has anti-inflammatory, mild-antibiotic, antacid, and protective qualities. It is commonly used in humans to treat ingidestion and diarrhea, but is sometimes used by veterinarians to treat the same symptoms in dogs. It is not safe to give to cats.

How It Works

The bismuth component of this drug seems to coat the intestines, protecting it from toxins. It also has weak antibacterial qualities against bacteria such as Heliobacter.

The salicylate component (salicylate is a substance similar to aspirin) seems to have a slight antiprostaglandin effect, assisting in the treatment of some types of diarrhea. Prostaglandins are hormone-like substances that promote the secretion of fluids, often causing diarrhea.

Storage Information

Store in a tightly sealed container at room temperature.

Missed Dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Side Effects and Drug Reactions

Bismuth Subsalicylate may result in these side effects:

  • Constipation
  • Gray or black stool

Bismuth Subsalicylate may react with these drugs:

  • Aspirin
  • Tetracycline derivatives
  • Protein bound drugs

USE EXTREME CAUTION WHEN ADMINISTERING BISMUTH SUBSALICYLATE TO CATS - This drug is not considered safe for use in cats. Use only under the direction of an experienced veterinarian.


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