By PetMD Editorial on Nov. 7, 2012

Drug Info

  • Common Name: Zantac®
  • Drug Type: H2 blocker
  • Used For: Stomach ulcers
  • Administered: Tablet, injectable
  • FDA Approved: No

General Description

Ranitidine is a histamine (H2) blocker that is used to prevent and treat stomach and intestinal ulcers in cats and dogs. It is often prescribed in the cases of gastritis and in the management of acid reflux disease to soothe inflammation and assist in healing. It also assists in stimulating the passage of food through the digestive tract.

Give this medication without food, as food will decrease it’s effectiveness.

How It Works

Histamine is a key component in the allergic reaction, causing inflammation and swelling. It can often cause stomach cramping and diarrhea as well. By inhibiting the H2 receptor, a receptor for histamine, Ranitidine reduces the output of stomach acid. This reduces the pH of the digestive system, giving the ulcer in the stomach time and a more favorable environment to rest and heal.

Storage Information

Store in a tight container at room temperature protected from light and heat.

Missed Dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Side Effects and Drug Reactions

Ranitidine may result in these side effects:

  • Vomiting
  • Diarrhea
  • Irregular heartbeat
  • Rapid breathing
  • Muscle tremors

Ranitidine may react with these drugs, as they absorb best in the presence of stomach acid:

  • Ketoconazole
  • Itraconazole

Please consult your veterinarian before giving these or any other drug or herbal supplement to your pet while on Ranitidine. It is best to give these medications at least two hours prior or following the use of Ranitidine.

DO NOT GIVE RANITIDINE TO LACTATING PETS

USE CAUTION WHEN ADMINISTERING THIS DRUG TO PETS WITH KIDNEY DISEASE, LIVER DISEASE, OR HEART RHYTHM ABNORMALITIES


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